Stool transplant instead of antibiotics



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Feces from healthy people can cure intestinal diseases

No matter in which way: Getting human feces administered is disgusting. In some cases where antibiotics fail, the so-called "stool transplant" seems to work wonders.

"Fecal therapy" is now called "stool transplant" - the content remains the same
Transmission of the intestinal flora, fecal therapy, stool transplantation, fecal bacterial therapy, stool transplantation: different names for one and the same method in which a sick person is to be treated with the faeces of a healthy person. At the German Society for Digestive and Metabolic Diseases it says: "Currently one of the most interesting topics in gastroenterology." Prof. Peter Galle, gastroenterologist at the university hospital said: "It is still an experimental procedure", but although the data is still thin and many If the questions are open, the approach is promising.

Help with rare dangerous illness
Appropriate therapy for horses under the name "transfaunierung" has been used for a long time. A horse that suffers from intestinal colic is instilled with a broth that has been mixed with the horse apples of a healthy animal. The subject received a lot of attention in human medicine when scientists from Amsterdam published a study in The New England Journal of Medicine earlier this year. The study was about people in whose intestines the notorious diarrhea germ Clostridium difficile had spread The intestinal wall is inflamed by the dangerous bacterium, which is resistant to many antibiotics, and the body is emaciated. The disease occurs relatively rarely, for example in 2012 in almost 800 patients in Germany, but 502 people died this year from such an infection.

Natural mix of bacteria
The Dutch study came to an astonishing conclusion after giving some of the patients an antibiotic and the other giving the stool to relatives. Only four out of 13 patients got healthy with the antibiotic. However, 13 out of 16 of the subjects with stool transfer were healed. Short-term complaints such as belching or abdominal cramps disappeared after a few hours. The professional association of resident gastroenterologists emphasized: "The procedure is new and only tried out at a few centers and a few patients." So far, there have been only a few cases of "individual healing attempts" in Germany, for example in Heidelberg and Ulm. Prof. Volkhard Kempf, director of the institute for microbiology at the University Clinic in Frankfurt, however, is convinced of "the curative effects of foreign stool: the beneficial bacteria contained in it contain the spread of the insidious germ and their administration leads to the normalization of the intestinal flora."

The administration of the "stool donation"
“The disgust factor” is a problem, according to Kempf. "The idea is not very aesthetic at first." Therefore, he can understand reservations well. To get the right dose, the "stool donation", between 100 and 200 grams, is diluted with saline to about 50 milliliters. The solution is then either over A colonoscope is inserted through the anus into the large intestine or through a nasogastric tube into the small intestine. According to microbiologist Kempf, there is much more to worry about diseases that could be transmitted with the feces than gastroenterologists. Gastroenterologist Galle also sees this danger: " Stool contains a complex mixture of different bacteria. It is almost impossible to say which are the good and which are the bad. "

Anonymous material, capsules or do-it-yourself
In an editorial by the Amsterdam scientists, US doctor Ciarán Kelly wrote: "The natural aversion to fecal therapy" could be reduced if the patient were offered anonymous material from donor banks. Microbiologist Willem de Vos from the University of Wageningen sees the solution rather to administer the beneficial bacteria of the intestine as an innocuous capsule. However, a corresponding medication is not yet on the market. And for those who don’t want to wait for the fecal pill or see an anonymous stool sample as a solution, there is still the " Do-it-yourself guide by Canadian gastroenterologist Michael Silverman, published in the Clinical Gastroenterology and Hepatology magazine. It describes how you can recolonise your intestine yourself with a stool donation, saline solution, hand mixer and an enema bag. (ad)

Image: Sebastian Karkus / pixelio.de

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Video: Fecal Microbiota Transplant for Clostridium difficile Infection in Cancer


Comments:

  1. Zuzil

    Full bad taste

  2. Meztikinos

    In my opinion, he is wrong. Let us try to discuss this. Write to me in PM, speak.

  3. Trahern

    You are wrong.

  4. Karan

    Yes it is all a fantasy

  5. Ramy

    Has casually come on a forum and has seen this theme. I can help you council.

  6. Jaidon

    Correct answer



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